Introduction/Background Advanced ovarian cancer is a complex disease and the management often requires complex surgery with known peri-operative risks. Prehabilitation programs include the patient’s time from diagnosis to treatment and aims to improve function and metabolic reserve with the hope of reducing these peri-operative complications. Multimodal prehabilitation interventions include exercise, nutritional optimisation, psychological support, frailty and lifestyle modification (e.g. smoking cessation).

Methodology A qualitative analysis of the prehabilitation programmes across four UK gynae-oncology cancer centres. Data was collected using reflective semi-structured interviews. Analysis included an inductive Braun&Clarke thematic analysis using NVivo to identify themes which were subsequently linked to the RE:AIM service evaluation framework.

Results 21 semi-structured interviews were conducted in total. Themes identified included;

1. Introduction (RE:AIM Implementation)

   • timing/volume/content of information. Mixed views on the most appropriate method for information giving but little understanding of the overall aims.

2. Engagement (RE:AIM Reach/Adoption)

   • Perceived need. Less likely to engage if have a strong social support or self-reported strong psychological baseline.

   • convenience of appointments has no impact on engagement.

   • accessibility of staff significantly improves engagement.

   • social anxiety impacts negatively on engagement.

3. Usefulness (RE:AIM Effectiveness)

   • repeated assessments improve engagement due to evidence of strength building.

   • lack of initial perceived need for psychological intervention but overwhelmingly positive once they engage.

4. Improvements (RE:AIM Maintenance)

   • Strong desire for more support with psychosexual/menopause health, regardless of age.

   • family involvement.

   • Continuity and follow up post treatment.

Conclusion In order to provide a personalised model of multi-modal prehabilitation for ovarian cancer it is of paramount importance to listen to patient opinions. This qualitative analysis shows a strong link between information giving and perceived need, with those who have a strong social network being less likely to engage. Clinicians must be mindful of psychosexual and post-menopausal health, regardless of age.

Disclosures None to declare.