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1239 Radio-pathological correlation for identifying positive inguinal lymph nodes in vulvar cancerbased on 7 cases and according to the experience of hassan 2 university hospital in Fes
  1. Zainab Benaboud
  1. CHU Hassan 2, Fes, Morocco

Abstract

Introduction/Background Vulvar cancer is an uncommon gynecological malignancy that predominantly affects older individuals, with a median age at diagnosis of 77 years. In over 90% of cases, it manifests as squamous cell carcinoma.

Diagnosis of vulvar cancer is based on clinical gynecological examination and biopsy.

Once the diagnosis has been made, staging becomes a crucial step in defining the therapeutic strategy. Lymph node involvement plays a central role in management. Several tools are therefore at our disposal, such as MRI, CT scan and inguinal ultrasound, alone or in association with fine-needle aspiration. This study focuses on the radiopathological correlation in the detection of positive inguinal lymph nodes in patients with squamous cell carcinoma of the vulva.

Methodology We conducted a retrospective study from 2020 to 2023 in the gynecology and obstetrics department of the Hassan 2 University Hospital in Fez. We identified 7 cases of squamous cell carcinoma of the vulva.

Results The median age of our cohort was 69 years. Risk factors identified included early sexual debut, immunosuppression and low socioeconomic status. All patients presented with vulvar swelling and an ulcerative and proliferative lesion, which was the reason for their consultation. Clinical examination revealed palpable lymph nodes on the same side as the lesion in two patients. All underwent thoraco-abdomino-pelvic computed tomography (CT), although in only one patient were suspicious lymph nodes observed on CT. The time from positive diagnosis to surgery was 4 weeks. Treatment consisted of total vulvectomy with bilateral deep and superficial inguinal lymph node dissection in 6 patients. Inguinal lymph node involvement was detected in two of them.

Conclusion In summary, the correlation between radiological and histopathological results of inguinal lymph nodes is a crucial aspect of the clinical management of vulvar cancer, influencing therapeutic decisions, and providing crucial information about the disease and its extent.

Disclosures The authors declare that they have no conflict of interest.

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