Introduction/Background Vulvar cancer (VC) is a rare malignant neoplastic disease, representing 3 to 5% of gynaecological cancers and occurring mainly in elderly women. Through this work, the authors aim to evaluate the epidemiological, clinical, histological and therapeutic profile and the prognosis of a series of patients with VC.

Methodology We conducted a retrospective study over a period of 5 years, from January 2018 until Decembre 2022. All cases of VC that were followed up in the Obstetrics and Gynaecology II Department of the Hassan II University Hospital in Fez-Morocco were included.

Results Twenty-eight cases of VC were listed. The average age was 61 years. 71,34% of the patients were menopausal, with an average menopause age of 47 years. 63,6% of patients were multiparous. Clinical symptomatology was dominated by the perception of a vulvar tumefaction and pruritus (92,3% and 84,26% respectively). The mean time of consultation was 15 months. The ulcerous-budding forms represent 55,41% of the cases with a frequent multifocal involvement. Vulvar biopsy was performed in 100% of cases and concluded to the diagnosis of squamous cell carcinoma in 100% of cases. Metastases were observed within three patients. In 61,54% of cases total vulvectomy with bilateral inguinal lymph node dissection was performed. Post-surgical complications are dominated by lymphoedema infection and suture release. Radiotherapy was indicated in 92.30% of patients.

Conclusion The prognosis of VC depends on several factors, especially tumor size, lymph node involvement and metastasis. All those factors may be directly related to consultation delay.

Disclosures All authors declare no conflicts of interest. This study did not receive any funding.