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1290 Prophylactic surgery as primary prevention of ovarian and breast cancer in the opinion of medical students in Poland
  1. Magdalena Anna Bizon1,
  2. Franciszek Lugowski2 and
  3. Maciej Olszewski1
  1. 1LUX MED Oncology Hospital, Warsaw, Poland
  2. 2Medical University of Warsaw, Warsaw, Poland


Introduction/Background Ovarian and breast cancers are neoplastic diseases with a genetic background. According to NCCN recommendations, risk-reducing salpingo-oophorectomy and mastectomy are procedures in primary prevention of these cancers in the case of a BRCA mutation.

The aim of the study was to analyze knowledge of medical students and their opinion about these prophylactic procedures.

Methodology A cross-sectional questionnaire consisting of 43 questions was completed by 200 medical students from Polish universities with mean age of 22.48±2.37 (range 19–34) years in every year of the study. The analyzed population was divided into two groups: 146 students with familiar background of neoplastic disease with mean age of 22.45±2.41 (range 19–34) years (group 1) and 54 students with no cancer in their families with mean age of 22.48±2.18 (range 19–33) years (group 2). Statistical analysis was performed using the R program.

Results In the opinion of 66.4% of students of the first group and 64.8% of the second one, genetic examination is very important in daily clinical practice. Prophylactic surgery is the most significant in primary prevention for 35.6% and 33.3% of groups 1 and 2, respectively (p<0.05). There is correlation between family history of neoplastic disease and encouraging patients to undergo prophylactic procedures in further medical life (p<0.05).

Female medical students would undergo risk-reducing salpingo-oophorectomy in the case of presence of a BRCA mutation in 71.3% and 66.7% of both groups, respectively, and mastectomy in 57.4% and 52.8%, respectively. Male medical students would encourage their partners in the case of presence of a BRCA mutation to undergo risk-reducing salpingo-oophorectomy in 51.6% and 38.9%, respectively, and mastectomy in 48.4% and 44.4%, respectively.

Conclusion Family history of neoplastic disease has an impact on knowledge and decisions about prophylactic surgery. Female medical students consider prophylactic procedures as a primary prevention of ovarian and breast cancer.

Disclosures The authors declare no conflict of interest.

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