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101 Ovarian dysgerminoma and pregnancy. A case report
  1. Syuzanna Babloyan1,2,
  2. Lilit Hovsepyan2 and
  3. Andranik Poghosyan2
  1. 11st Department of OBGYN, Yerevan State Medical University after M.Heratsi, Yerevan, Armenia
  2. 2Erebouni MC, Yerevan, Armenia


Introduction/Background Objectives: Ovarian dysgerminoma are malignant ovarian germ-cells tumors. They are characteristically solid and well-encapsulated with an average diameter of 15 cm. Its association with pregnancy is extremely rare; the incidence is about 0.2–1 per 100,000 pregnancies.

Methodology Methods: We presented a case of a 32 years old patient, G2, P2, who was referred to our unit for incidentally detected at 33 weeks of gestation right side ovarian mass. Her life history was unremarkable. Ultrasound examination revealed a 33 weeks singleton healthy fetus, and a purely solid ovarian mass 24,5 x 14,5 x 20,0cm on right side, divided into different lobules, with irregular internal echogenicity, with smooth lobulated contours and well defined borders, and richly vascularized at color/power Doppler examination – score 4. The free fluid in pouch of Douglas was revealed. CA- 125 was 335 U/ml, LDH- 500U/I

Results Results: Cesarean section was performed at 34 weeks of gestation, after fetal lung maturation with corticosteroids. The healthy premature baby was born, 2250.0 gram. During operation we revealed a huge solid tumor on right adnexa, free peritoneal fluid in pouch of Douglas and abdominal cavity, tumor infiltration on the surface of the pelvic peritoneum. Optimal cytoreduction includes total abdominal hysterectomy with bilateral adnexectomy were performed. The patient‘s postoperative course was unremarkable. The histological examination revealed a right ovarian dysgerminoma, stage IIB by FIGO. She received 6 course of adjuvant chemotherapy. Follow-up with ultrasound scans, CA 125 and LDH tumor marker rate evaluation every 6 months.

Conclusion Conclusions: The standart ultrasound examination has highly effectiveness in detection of malignant ovarian tumors. Treatment strategy in women with ovarian dysgerminoma should be discussed and structured on an individual basis. High survival rates can be achieved in patients treated with appropriate surgery and adjuvant chemotherapy.

Disclosures None.

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