Introduction/Background The rate of serious complications associated with a laparoscopic approach is overall low. Up to one-half of complications occur at the time of abdominal access for camera or port placement. Complications can also arise from abdominal insufflation, tissue dissection, hemostasis. These surgical videos aim to demonstrate uncommon complications in two patients.

Methodology A step-by-step explanation of the procedures which were performed on the patients using these videos.

Results The article provides information about the authors' clinical observation of two patients diagnosed with port-site metastasis after laparoscopic surgery for endometrial and cervical cancer. One of them is the case of a 64 -year-old woman with postmenopausal bleeding. Preoperative endometrial biopsy and pelvic magnetic resonance imaging had not been performed. Laparoscopic hysterectomy and bilateral salpingo-oophorectomy have been carried out. Postoperative pathology examination has revealed FIGO Grade 2 Stage 1B endometrioid endometrial adenocarcinoma. September 2019 PET – CT scan: 7 cm high hypermetabolic malignant lesion of the anterior abdominal wall. 6 courses of adjuvant chemotherapy were administered. April 2020 PET – CT scan: 9 cm high hypermetabolic malignant lesion of the anterior abdominal wall. Port-site metastasectomy and hernioplasty with mesh were carried out in the Department of Gynecological Oncology, Azerbaijan Medical University. Pathological examination of the material revealed a high-grade malign tumor with a negative surgical margin. Detailed information of the second patient will be explained during the presentation.

Conclusion These cases demonstrate that PSM is an uncommon complication of laparoscopy, associated with wound events and a poor prognosis. PSM prevention plays a crucial part in the overall care of patients with gynecologic malignancies who undergo laparoscopic procedures.

Disclosures Endometrium, Port-site Metastasis, Laparoscopy.