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807 Results in carcinomatosis peritoneal in endometrial cancer: is it the same as ovarian cancer?
  1. Mar Bort Gimeno,
  2. Teresa Micaela Arrufat Conesa,
  3. Anna Serra Rubert,
  4. Maria Teresa Climent Marti and
  5. Antoni Llueca Abella
  1. General University Hospital of Castellon, Castellon, Spain

Abstract

Introduction/Background Endometrial cancer is a rare cause of peritoneal carcinomatosis. The aim of our study is to describe and analyse the outcomes of who underwent surgery for endometrial cancer with peritoneal carcinomatosis at the Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery (MUAPOS) of the General University Hospital of Castellon from 2012 to 2022.

Methodology This is a retrospective observational study, which included patients who underwent surgery for peritoneal carcinomatosis of endometrial origin at MUAPOS between 2012 and 2022. A descriptive analysis of the data of the 20 patients included during this period was performed.

Age, histological type and grade, FIGO stage, intraoperative peritoneal carcinomatosis index (PCI) and type of cytoreduction obtained were studied. Overall survival and disease-free interval were calculated.

Quantitative variables were defined as median and range and qualitative variables as frequencies and percentages. Survival analysis and disease-free interval were measured using the Kaplan-Meier method.

Results The median age was 68 years (52 - 82 years). In terms of histology, the majority were endometrioid (75%). In relation to histological grade, most of the tumors were poorly differentiated (65%).

As per the FIGO staging, 6 patients had stage III (2-IIIA, 2-IIIB, 2-IIIC) and 14 patients had stage IV (7-IVA and 7-IVB).

The median intraoperative PCI was 10.5 (3 - 35). In 4 patients (20%) optimal cytoreduction was not accomplished, while in 16 patients (80%) optimal cytoreduction was achieved.

The median disease-free interval was 10 months (CI 2.56 - 17.43). The median overall survival was 7 months (CI 1.32 - 12.68).

Conclusion Endometrial cancer is a rare entity of peritoneal carcinomatosis. It presents a very poor prognosis, with a short disease-free interval and a short median survival compared to ovarian cancer, which shows the need for studies to establish other treatment options that improve the prognosis of our patients.

Disclosures The authors report no conflicts of interest in this work.

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