Article Text

Download PDFPDF
912 Occurrence of iron deficiency anemia and its subtypes in gynecological oncology patients: diagnosis and way forward
  1. Aliya Begum,
  2. Uzma Chishti,
  3. Usman Muhammad,
  4. Anam Riaz and
  5. Amir Raza
  1. Aga Khan University Hospital, Karachi, Pakistan


Introduction/Background In preoperative gynecologic cancer patients, iron deficiency anemia (IDA) is a disease that can have major impact on surgical outcomes. It is essential for efficient therapy and better patient outcomes to comprehend many forms of IDA within this patient population. There are two types of IDA: functional and absolute. This study aims to determine prevalence of iron deficiency anemia and its subtypes among patients with gynecological malignancies.

Methodology This study was prospective cross-sectional and included 80 patients who had cancer Surgery at Aga khan University Hospital between April-October 2023. Anemia was defined as Hb of less than 11g/dl. Absolute Iron Deficiency was labelled when ferritin level of less than 30ng/ml & transferrin saturation (TSAT) less than 20% and Functional Iron Deficiency when serum ferritin ranged from 30ng/ml to 500ng/ml with Transferrin saturation of less than 50%.

Results The study involved eighty patients. Participants’ average age was 53.53 years, and their average BMI was 29.20 kg/m2. Seventy-one percent of the patients were postmenopausal. Ovarian and uterine cancers accounted for 48.8% and 40% of all malignancies, respectively. Synchronous ovarian and uterine cancers affected three women. Pre-operative hemoglobin had a mean value of 11.87±1.09. Sixteen patients (20%) were found to have iron deficiency anemia. Out of the sixteen patients who were diagnosed with iron deficiency anemia, eleven (66.7%) had functional iron deficiency anemia, and five (31.3%) absolute iron deficiency. Ovarian and uterine cancers including synchronous ones had functional Iron deficiency.

Conclusion We discovered that functional iron deficiency anemia accounted for most anemic cases in our study. To accurately identify the type of iron deficiency anemia, people with anaemia must have iron testing, and the patient‘s treatment plan should be tailored to type of anemia that has been recognized. Patients with ovarian and uterine cancer should receive special attention for best possible care.

Disclosures We don’t have any disclosures.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.