Introduction/Background The aim of our study was to evaluate the place of closure surgery after concomitant radiochemotherapy as well as the complications of these treatments for advanced stage cervical cancer.

Methodology Patients with the following inclusion criteria were studied: stage IB2-IVA cervical cancer; tumor initially radiologically limited to the pelvic cavity; CCR including 45 Gy of external radiotherapy to the pelvic cavity combined with chemotherapy followed by utero-vaginal brachytherapy; closure surgery within 2 months after CCR with at least one hysterectomy.

Results 12 patients operated on between January 2018 and November 2023 at the Department of Obstetric Gynecology I CHU Hassan II, FES were included in this study. Complete sterilization of the cervix was found in 4 patients . absence of pelvic and lombo-aortic lymph node invasion in all patients . 2 patients required postoperative chemotherapy for recurrence (pelvic mass) and only one patient required postoperative barrier therapy. All patients are alive.

Conclusion The therapeutic impact of this surgery remains unproven. The presence and size of tumour residue and the presence of lymph node involvement were the most important prognostic factors. These results suggest that longer survival for patients treated with RCC for advanced cervical cancer could be achieved if the complete response rate in the irradiated areas (cervical and lymph node) could be improved, as well as by earlier detection of lumbo-aortic involvement.

Disclosures Les auteurs ne déclarent pas un conflit d’intérêt.