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775 Prevalence and determinants of anemia in cervical cancer patients: a one-year retrospective study
  1. Shoon Mya Aye
  1. Karuna Compassionate Care Center, Yangon, Myanmar

Abstract

Introduction/Background Anemia is a prevalent condition among cancer patients, particularly those with gynecologic malignancies. Its causes are multifaceted, including tumor-specific and treatment-related factors, chronic inflammation, acute blood loss, and malnutrition. This study aimed to assess the prevalence and factors associated with pretreatment anemia among cervical cancer patients.

Methodology The study retrospectively analyzed the clinical data of 50 cervical cancer patients from Karuna Oncology Clinic between March 2022 and March 2023. The inclusion criteria were all patients with cervical cancer who gave consent. Those who had already received any cancer treatment and cases complicated by other primary tumors were excluded. A binary logistic regression model was used to identify covariates affecting the outcome variable

Results The study found that 48% of the cervical cancer patients had anemia before treatment, with 14% having severe anemia. The majority of the patients were Buddhists, urban dwellers, and married, with a mean age of 52.46 years. About 30% of the patients had a history of substance use, and 80% were in the advanced stages (IIB, III and IV). The occurrence of anemia was significantly associated with the advanced stages of cervical cancer [OR= 2.500, 95% CI (1.710–3.654)] [p < 0.001].

Conclusion The study concluded that anemia is a common condition among cervical cancer patients, with a significant association with the advanced stages of the disease. This finding underscores the importance of early detection and treatment of both cervical cancer and anemia, as they can significantly affect the patient’s quality of life. Further research is needed to explore strategies for managing anemia in patients with advanced cervical cancer. However, the findings should be interpreted in light of the study’s limitations, including its retrospective design and the relatively small sample size.

Disclosures I have no potential conflict of interest to report.

Abstract 775 Table 1

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