Article Text

Download PDFPDF
655 Retrospective analysis of the clinical outcome of uterine cervix cancer patients with operable disease
  1. Vladyslav Sukhin1,
  2. Olexandr Mikhanovskyj1,
  3. Olena Sukhina1,2,
  4. Hanna Hranovska1,
  5. Victoria Kovaltchuk1,
  6. Yurii Shen3,
  7. Heorhii Shen4,
  8. Dmitrii Sumtsov5,
  9. Hanna Lohvyniuk6,
  10. Oksana Onikiienko7,
  11. Alina Koshmerynska7,
  12. Iryna Sokur8,
  13. Nina Mohyla8 and
  14. Viacheslav Maksymovskyi9
  1. 1Grigoriev Institute for medical Radiology and Oncology NAMS Ukraine, Kharkiv, Ukraine
  2. 2Kharkiv National medical University, Kharkiv, Ukraine
  3. 3Chernihiv Medical Center of Modern Oncology, Chernihiv, Ukraine
  4. 4Chernihiv regional hospital, Chernihiv, Ukraine
  5. 5Public Non-Profit Institution of Sumy Regional Council «Sumy Regional Clinical Oncology Dispensary», Sumy, Ukraine
  6. 6Medical Institute of the Sumy State University, Sumy, Ukraine
  7. 7Zhytomyr Regional Clinical Oncology Center, Zhytomyr, Ukraine
  8. 8Kherson Regional Oncological Center, Kherson, Ukraine
  9. 9Odesa National Medical University, Odessa, Ukraine


Introduction/Background Radical hysterectomy with pelvic lymphadenectomy remains the standard surgical procedure in treatment of patients with early cervical cancer. The choice of surgical approach depends on clinic experience. The discussion, concerning the surgical approach in cervical cancer patients after the publication of the data of multicentral study SUCCOR, started again among the colleagues.

Due to experience and Ukrainian guidelines, in selected case of stage IB – IIB it is also advisable to start the treatment with preoperative chemotherapy or chemoradiation therapy, which leads to the tumor devitalization, tumor volume decrease and enable more ablastic surgery for better patients outcome.

Methodology There were analysed treatment results of the 148 cervical cancer patients stages IA-IIB, IIIB T1a-2bN0–1M0, who underwent treatment in 6 oncological clinics of Ukraine.

Results Regardless the stage of disease, 87 of 148 (58.8%) patients have received adjuvant course of EBRT, according to the pathology data at surgical specimen. The relapsed disease was detected in 15 of 148 (10.1%) patients. All the 8 patients, who underwent laparoscopic surgery as a first step of the treatment, had stage IB1 and at follow-up in them there was not detected relapsed disease.

Conclusion It is challenging to comment on laparoscopic approach, because of the limited number of patients in this study. However, in all of them, there were not detected relapsed disease at follow-up of 2 years. Preoperative chemoradiation therapy promote the increase of patients survival.

Disclosures Nothing to disclose.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.