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Review
Assessing minimally invasive simple hysterectomy in low risk cervical cancer: set up for the LASH trial
  1. Nicolò Bizzarri1,
  2. Nadeem R Abu-Rustum2,
  3. Marie Plante3,
  4. Pedro T Ramirez4,
  5. Luis Chiva5,
  6. Henrik Falconer6,
  7. David Cibula7,
  8. Denis Querleu1,
  9. Francesco Fanfani1,8,
  10. Anna Fagotti1,8 and
  11. Giovanni Scambia1,8
    1. 1 UOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
    2. 2 Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
    3. 3 Department of Obstetrics and Gynecology, Centre Hospitalier Universitaire de Quebec, Quebec, Quebec, Canada
    4. 4 Department of Obstetrics and Gynecology, Houston Methodist Hospital, Houston, Texas, USA
    5. 5 Clinica Universidad de Navarra Departamento de Ginecologia y Obstetricia, Pamplona, Spain
    6. 6 Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden
    7. 7 Department of Obstetrics and Gynecology, University of Prague, Prague, Czech Republic
    8. 8 Università Cattolica del Sacro Cuore, Rome, Italy
    1. Correspondence to Dr Nicolò Bizzarri; nicolo.bizzarri{at}yahoo.com

    Abstract

    After the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, open surgery has become the standard approach for radical hysterectomy in early stage cervical cancer. Recent studies assessed the role of a non-radical approach in low risk cervical cancer and showed no survival difference compared with radical hysterectomy. However, there is a gap in knowledge regarding the oncologic outcomes of minimally invasive simple hysterectomy in low risk cervical cancer. This review offers an overview of the current evidence on the role of the minimally invasive approach in low risk cervical cancer and raises the need for a new clinical trial in this setting.

    • Hysterectomy
    • Cervix Uteri
    • Laparoscopes
    • Laparotomy
    • Robotic Surgical Procedures

    https://doi.org/10.1136/ijgc-2024-005941

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      Footnotes

      • X @pedroramirezMD, @frafanfani

      • Contributors NB, AF, NRA-R, DQ, and GS: conceptualization. All authors: literature search. PTR: writing and editing. All authors: writing and revising. AF and GS: supervision. NB is the guarantor.

      • Funding Dr. Abu-Rustum was supported in part through the National Institutes of Health/National Cancer Institute Cancer Center Support Grant (P30 CA008748).

      • Competing interests None declared.

      • Provenance and peer review Not commissioned; externally peer reviewed.