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Abstract
Introduction Human papilloma virus is the commonest sexually transmitted infection among young adult, fortunately enough most of the individuals infected with human papilloma virus are asymptomatic and able to clear the virus so long as they have no innate or acquired immune deficiency. Though it is not uncommon to see genital warts of small-medium sized, it is very rare to find giant genital warts which cannot be managed with topical ablative therapy. Human immune-deficiency virus (HIV) co-infection is the most important contributor for locally aggressive vulvar condyloma acuminatas (Buschke Lowenstein tumor).
Methods ‘/Here I report a case series of giant vulvar condyloma accuminata (vulvar wart) of three cases with two of the cases of Sero-positive for HIV on HAART (highly active anti-retroviral therapy) CD4 counts of all of them under 500 cells/ul , including a ten year old pre-menarche female who had also a giant wart which was not amenable for local ablative treatments. referred from regional hospitals for possible vulvectomy in our teaching hospital.
Results The surgeries were skinning vulvectomy with huge tumor bleeding at the base with no major intra-operative complications. All of the cases had superficial wound infections and improved significantly with a local wound care.
Conclusion/Implications HPV associated vulvar genital condyloma accuminata, in HIV seropositive patients can be beyond local ablative treatments and delay in referral and care for these cases can cause significant impact in their quality of life. The surgical care of giant warts needs gynecologic oncologist surgical expertise.
