Article Text
Abstract
Introduction We report the oncological outcomes in patients with advanced ovarian cancer who had bowel surgery which was performed by gynecologic oncologist (GO) during maximal cytoreductive surgery and compared the outcomes with those of bowel surgery performed by general surgeons (GS).
Methods Patients who were FIGO stage I-IV ovarian cancer and had bowel surgery during maximal cytoreductive surgery were eligible. Patients were divided into two groups according to whether bowel resection was performed by GO or GS. In both groups, GO were mainly involved in debulking procedures. Perioperative and survival outcomes were compared between two groups.
Results A total of 439 patients were eligible. 82 patients received large bowel surgery by GO, and 357 patients by GS. The proportion of patients who underwent PDS was higher in GO group than in GS group (80.5% vs 70.9%, p =0.057). The residual disease after maximal cytoreductive surgery did not differ between two groups (P=0.281). The distribution of anastomotic sites of large bowel resections were not different between two groups. There was no significant differences in progression-free and overall survival between two groups. In a multi-variate Cox analysis, Time of surgery (PDS vs. IDS, HR 2.124, 95%CI 1.037–4.348, p=0.039) and residual diseases (R0 vs. non-R0, HR 2.133, 95%CI 1.001–4.547, p=0.050) were associated with survivals. Bowel surgery specific complications did not differ between two groups.
Conclusion/Implications Large bowel surgery performed by GO was feasible and safe. We showed equivalent oncological outcomes when compared with those by GS during maximal cytoreductive surgery for advanced ovarian cancer.