Introduction Diagnosis of ovarian tumors are challenging and requires a pathologist expertise in its diagnosis process. Intraoperative frozen section serves as an important diagnostic tool for intraoperative settings. However, accuracy remains an important factor in frozen section diagnosis. This study is comparing frozen section diagnosis to paraffin block as the gold standard in Prof. Dr. R.D. Kandou Regional Hospital.

Methods This cross-sectional study is conducted in Prof. Dr. R.D. Kandou Regional Hospital during June 2021 to June 2022 obtained by medical records of all patients undergoing intraoperative frozen section and will be compared with paraffin block. Data are then analyzed in IBM Statistics SPSS 25.

Results Comparison of each category between frozen section and paraffin block revealed sensitivity of 83,5%, 100.0%, and 76.9% with specificity of 90.4%, 90.0%, and 95.5% for benign, borderline, and malignant diagnosis respectively. A 100% sensitivity for borderline diagnosis is the result of no false negative results in all 13 borderline cases. All results are found to be significant (p<0.001). Among 28 patients who were diagnosed with borderline cases by frozen section, the final pathological diagnosis was upgraded to malignant 14.3%, 46.4% remained borderline diagnosis and 39.3% diagnosed benign.

Conclusion/Implications Intraoperative frozen section is an important tool that can help manage the patient. But intraoperative frozen section must be calibrate to ensure the accuracy.