You are here

  • Home
  • Archive
  • Volume 33, Issue Suppl 4
  • EP201/#746  Association between estrogen receptor/progesterone receptor status and risk factors in postmenopausal women with endometrioid type endometrial cancer

Article Text

Article menu

Download PDFPDF

ePoster Viewing
AS08. Gynecologic pathology/cytology and disease pathogenesis
EP201/#746  Association between estrogen receptor/progesterone receptor status and risk factors in postmenopausal women with endometrioid type endometrial cancer
Free
  1. Jisoo Lee1,
  2. Eunhyun Lee2,
  3. Minseong Choi2,
  4. Minjeong Park2,
  5. Yong-Il Ji2 and
  6. Su-Ji Kim3
  1. 1Haeundae Paik University, Obstetrics Gynecology, Busan, Korea, Republic of
  2. 2Inje University, Haeundae Paek Hospital, Obstetrics and Gynecology, Busan, Korea, Republic of
  3. 3Inje University Haeundae Paik Hospital, Department of Obstetrics and Gynecology, Busan, Korea, Republic of

Abstract

Introduction Estrogen receptor(ER)/Progesterone receptor(PR) status has been known as a prognostic factor in endometrial cancer. Our study aimed to analyze the association between ER/PR status and risk factors including stage, histologic grade, myometrial invasion, lymphovascular space invasion(LVSI), lymph node(LN) metastasis, and cytology washing results in order to determine their relevance in postmenopausal women with endometrioid type endometrial cancer.

Methods We retrospectively analyzed 114 postmenopausal patients who underwent staging surgery after being diagnosed with endometrioid type endometrial cancer at Haeundae Paik Hospital between 2010 and 2022. The associations between ER/PR status and risk factors were compared using the chi-square test.

Results ER status showed statistically significant associations with histologic grade, myometrial invasion, LVSI, LN metastasis, and the results of washing cytology (p-values were 0.001, 0.016, 0.033, 0.018, and 0.013, respectively). On the other hand, PR status showed only significant association with histologic grade statistically (p-value 0.001).

Conclusion/Implications ER status was observed to have a more significant role as a prognostic factor than PR in postmenopausal endometrioid type endometrial cancer.

https://doi.org/10.1136/ijgc-2023-IGCS.283

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.