Introduction In Republic of Kazakhstan, endometrial cancer among malignant tumors occupies the 9th ranking position, and in the structure of gynecological cancer, the 3rd place, about 1000 cases of this disease are detected annually. The main method of treatment for EC is surgical treatment, with mandatory removal of regional lymph nodes (LN) for preventive purposes, regardless of their morphological state. However, prophylactic lymphadenectomy did not justify itself. Plenty of evidence suggests an improvement in survival only in groups of patients who have been diagnosed with metastatic changes in the lymph nodes.
Methods In the period from January 1, 2021 to December 30, 2021, 37 patients with detection of sentinel lymph nodes were registered in KazIOR. We collected retrospective data from history of diseases.
Results The mean age of the patients was 52 years. The average body mass index of patients was 30.2 kg/m². Preoperative assessment of endometrial cancer risk groups showed: low risk in 19 (51.3%) patients, intermediate risk in 11 (29.7%) patients, high risk in 7 (18.9%) patients. Complete pelvic and para-aortic lymph node dissection was performed in 7 (18.9%). In 30 (81%) patients, at least one sentinel lymph node was successfully mapped. 7 (18.9%) patients had positive nodes. In 37 patients, no postoperative complications were detected. The final histology revealed: 31 (83.7%) patients had endometrioid adenocarcinoma, 6 (16.2%) had clear cell carcinoma.
Conclusion/Implications This study confirms the feasibility of the SLN procedure to assess recurrence risk in patients with early EC and the safety of sentinel lymph node detection.
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