Introduction Cervical cancer is the most common gynecological malignancy in Nigeria. HPV vaccines are about to be rolled out for young girls aged 9–14 years in Nigeria.The key issue remains, how to deal with vaccine hesitancy and ensure adequate uptake. This study aims to assess the awareness level of Cervical cancer and HPV vaccination, as well as attitude towards Vaccine uptake.

Methods A Focus Group Discussion was held with a representative sample of 100 Nigerian women aged 35–55 years, using a guide to assess their knowledge of Cervical cancer, HPV Vaccination, and willingness to consent to the uptake of vaccine by their young girls aged 9–14 years. Transcribed data was analyzed by Coding the text.

Results Only 10 women had prior knowledge of Cervical Cancer, none of the women had ever undergone a screening test and none of them had prior knowledge of the HPV Vaccine. After the Focus group discussion, more than half of the women displayed proper understanding of the disease and the need for Vaccination, 5 women from the Sample population displayed willingness to Champion the cause.

Conclusion/Implications From this study we can deduce that proper knowledge is key, an aware population can make health-conscious choices when given the right tools. It is however important to consider proper messaging and the education level of the Communities. Furthermore, pre-bunking myths help to reduce the incidence of Vaccine hesitancy.