Introduction/Background To analyze the risk of cervical pre-invasive disease in women with post-coital bleeding (PCB)

Methodology In our study, the findings and results of colposcopic examination of 185 women who were admitted to Hacettepe University Faculty of Medicine Hospital Obstetrics and Gynecology Department between January 2018 and December 2022 and who were evaluated for PCB and who underwent colposcopic examination were evaluated retrospectively. Primary outcome was to find out to risk of CIN 2 and above pre-invasive disease in woman with PCB

Results The median age of the women included in the study was 38 (min: 19-max: 64). 85.4% had cervical cytology results (158/185). 4.9% of cytology results evaluated were ASC-US (9/185) and 1.1% were LSIL (2/185). 60% of the women had Human Papilloma Virus (HPV) screening results. 15.6% of the women were HPV test positive (4.8% HPV 16–18, 6.5% other high-risk HPV, and 4.3% low-risk HPV).

The most common pathological finding detected with the direct examination during the colposcopic examination was ectropion with 18.4% (34/185). Cervical biopsy was performed in 48.6% of the evaluated women. In most of the biopsies performed (86.6%), a single sample was taken.

While CIN 2 was detected in 1.1% of the women (2/185) and the most common histological result was cervicitis (73/185). Two women whose biopsy showed CIN 2 were also positive for HPV infection . Whereas CIN 2 lesion was found in 2 (11%) of 18 patients with positive HPV test ın the biopsy group, CIN 2+ was not dedected in any of the HPV negative patients (P=0.038).

Conclusion The rate of detecting cervical lesions through colposcopic examination is low in women experiencing PCB complaints.The utilization of HPV testing in the triage of PCB can reduce unnecessary colposcopic examinations and cervical biopsies.

Disclosures The authors have no conflict of interest related this research