Introduction/Background The survival in early stages of cervical cancer has improved dramatically. An issue of of quality of life after surgery has become relevant. The aim of this study is to evaluate the quality of life of patients who have undergone radical or less radical surgery of cervical cancer.

Methodology Between 2007 and 2011, 100 patients undergoing surgery for cervical cancer (stage IA2-IB2) were included. Patients filled a quality of life questionnaires EORTC QLQ–C 30 and CX 24 before surgery, 6, 12 and 120 month after surgery. For final evaluation at follow-up at 120 months 54 patients were used. Of them 23 underwent conservative surgery (laparoscopic lymphadenectomy plus simple trachelectomy/simple hysterectomy, CONS group) and 31 radical surgery (abdominal radical hysterectomy type C1 - RAD group).

Results At 6 month post surgery RAD group exhibited more menopausal symptoms and worse Physical functioning compared to CONS. Compared to preoperative period patients in CONS group had more symptoms regarding lymphoedema and neuropathy and slightly worse Physical functioning while they had improved outcomes in Role, Emotional and Social functioning. In RAD group patients had more Sexual worries. At 120 month post surgery RAD group exhibited worse outcomes in Lymphoedema, Peripheral neuropathy, Postmenopausal symptoms, Fatigue, Pain and Physical functioning compared to CONS group.

Conclusion Cervical cancer treatment is associated with negative impact on quality of life, which can persist for years following treatment. Most of the women included in our sample reported worsening in the areas of role functioning, emotional functioning, pain, peripheral neuropathy, menopausal symptoms and sexual activity as a consequence of treatment for cervical cancer. Radical group suffered from more symptoms.

Disclosures This study has been supported by Cooperatio program, Maternal and Childhood Care No. 207035, 3rd Medical Faculty, Charles University.