Introduction/Background The sentinel lymph node (SLN) mapping may have particular value in endometrial cancer (EC) because a therapeutic effect of lymphadenectomy per se is still unproven.

Methodology From March 2017 through December 2022, 114 women with apparently early stage EC underwent laparoscopic hysterectomy including ICG fluorescence SLN mapping. In all of the cases we use the IMAGE1 S™ Rubina – K. STORZ.

Results In all patients more than ≥1 SLNs was identified. In 94 (84.2%) patients bilaterally and in 20 (14.8%) patients unilaterally. All SLN-positive patients had pelvic SLNs. Lymph node metastases were detected in 6 patients (5.2%).

Conclusion With the standardization of the technique we managed to reproduce the high total and bilateral SLN mapping using cervical ICG injection and NIR fluorescence.