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  • #965 First impressions of patients‘ perspectives of prehabilitation as part of the kore-innovation trial: the first prospective clinical trial to assess a perioperative pathway to reduce postoperative complications in ovarian cancer

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Poster/ePoster Sessions
14. Organization of Gynaecological Cancer Care
#965 First impressions of patients‘ perspectives of prehabilitation as part of the kore-innovation trial: the first prospective clinical trial to assess a perioperative pathway to reduce postoperative complications in ovarian cancer
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  1. Marlene Misu Lee1,
  2. Jalid Sehouli1,
  3. Melisa Guelhan Inci-Turan1,
  4. Eva Schnura2,
  5. Philipp Harter2,
  6. Radoslav Chekerov1,
  7. Julia Klews3,
  8. Stephanie Roll4,
  9. Stefan Willich4,
  10. Marlen Brinkmann5,
  11. Phil Niggemann6,
  12. Fabian Maximilian Meinert6,
  13. Adak Pirmorady-Sehouli7,
  14. Thomas Reinhold4,
  15. Manuela Zimmermann8,
  16. Henriette Thorau3,
  17. Aleksander Runge1,
  18. Lena Zwanzleitner9,
  19. Andrea Krull10 and
  20. Stephanie Schneider2
  1. 1Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Gynecology with oncologic Surgery, Augustenburger Platz 1, 13353 Berlin, Germany, Berlin, Germany
  2. 2Evangelische Kliniken Essen Mitte, Department of Gynecology and Gynecological Oncology, Henricistraße 92, 45136 Essen, Germany, Essen, Germany
  3. 32. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Pflegedirektion, Charitéplatz 1, 10117 Berlin, Germany, Berlin, Germany
  4. 4Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute for Social Medicine, Epidemiology and Health Economics, Charitéplatz 1, 10117 Berlin, Germany, Berlin, Germany
  5. 5Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Physical Medicine and Rehabilitation; Hindenburgdamm 30, 12203 Berlin, Germany, Berlin, Germany
  6. 6Charité Universitaetsmedizin Berlin, Berlin, Germany
  7. 7Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Psychosomatic Medicine, Hindenburgdamm 30, 12203 Berlin, Germany, Berlin, Germany
  8. 8Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Pflegedirektion, Charitéplatz 1, 10117 Berlin, Germany, Berlin, Germany
  9. 9Techniker Krankenkasse, Hamburg, Germany
  10. 10Association for Gynecological Cancers Germany, Neumünster, Germany

Abstract

Introduction/Background Preferred treatment for ovarian cancer is a primary debulking surgery associated with surgical stress and high levels of morbidity.

Implementing the Enhanced Recovery After Surgery (ERAS) pathway has shown improved postoperative outcomes. However, preoperative screening for risk factors and optimization of general health status is not widely implemented, even though they could increase postoperative reconvalescence by improving baseline health status. Patient’s compliance is critical for a successful implementation, which makes understanding their perspective valuable. We report preliminary results of patients’ perspective on prehabilitation.

Methodology As part of our ongoing clinical trial, we implement an innovative multimodal perioperative care pathway consisting of a trimodal prehabilitation in combination with the established ERAS pathway for ovarian cancer patients undergoing primary debulking surgery. The trimodal prehabilitation consists of a personalized, targeted nutrition-, physical fitness-, and mental health intervention, following a comprehensive baseline assessment. At the end of prehabilitation, before undergoing surgery, patients are asked about their perspective on prehabilitation by a closed questionnaire.

Results Data of 131 patients were available for preliminary analysis. When asked which part of prehabilitation was most supportive, 53% reported the overall package, 36% physical activity, and 12% the nutrition intervention to be most helpful. 11% felt most supported by the mental health coaching, and only 4% did not feel supported by prehabilitation. Furthermore, 40% reported feeling more physically capable after prehabilitation, vs. 56% who felt the same, and 4% felt less physically capable. Furthermore, 59% reported feeling mentally strengthened by prehabilitation, 37% reported the same level as before, and only 3% reported feeling worse.

Conclusion Preliminary results suggest that patients seem to respond well to a trimodal prehabilitation program. The overall package seems best received, followed by physical fitness and nutrition advice. A lot of patients report feeling physically more capable, as well as mentally strengthened after prehabilitation.

Disclosures KORE-INNOVATION is funded by the ‘Innovationsfonds’ of the ‘Gemeinsamer Bundesausschuss’ (01NVF18021)

https://doi.org/10.1136/ijgc-2023-ESGO.862

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