Introduction/Background Different reconstruction options are available when large defects that require reconstruction occur. In this study, we present the treatment strategy and results for patients who underwent reconstruction after resection for gynecological cancer in the vulva and perineum. Material and Methods: A total of 22 patients who underwent reconstruction between April 2018 and April 2022 were included in this retrospective study. Demographics and clinical data,

Methodology A total of 22 patients who underwent reconstruction between April 2018 and April 2022 were included in this retrospective study. Demographics and clinical data, the resection operation, characteristics of the defect, and the reconstruction methods applied were evaluated. Postoperative treatment strategy and complication rates were evaluated.

Results The mean age was 58.3±16.2 (41–90) years. 88.9% of the patients had additional diseases. Pelvic exentration was performed in 5 (27.8%) patients, anterior resection in 2 (11.1%) patientsand vulvectomy in 11 (61.1%) patients. The most common malignancy was squamous cell carcinoma Reconstruction was performed with Bilateral fasciocutaneous flap in 15 (68.1%) patients, Unilateral fasciocutaneous flapin 4 (16.7%) patients, Rectus abdominis myocutaneous flap in 1 (4.5%) patient.and skin graft in two (9.0%) patient. Wound complications occurred in 7 (31.8%) patients, partial flap necrosis in one (5.6%) patient, and recurrence in one (9.0%) patient in the long term.

Conclusion Gynecological oncological radical resections are an effective way to treat gynecological malignancies and premalign lesions.Reconstructive surgery could be required.

The technique of reconstruction should be chosen carefully and a multidisciplinary approach should be used when needed. Patients who underwent vulvectomy are at a higher risk of surgical site complications.

Disclosures There are no known conflicts of interests among the authors.