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Abstract
Introduction/Background Choriocarcinoma is a malignant neoplasm with its origin in the trophoblast. It can be found after every pregnancy, but especially after a pregnancy complicated by mola hydatidosis (complication in 2–3% of all molas).
Methodology A 25-year-old female patient was admitted to our hospital for profuse bleeding 30 days after cesarean delivery.
The patient is an otherwise healthy young woman who was giving birth for the third time . Previous deliveries were Sectio Caesarea.
After the cesarean section, she had a curving curve and 4 exploratory curettages were performed.
The histopathological findings of the first three exploratory curettages indicated a normal endometrium, while the findings of the fourth exploratory curettage were hydatidiform moles. The primary biochemical marker, used in treatment and prognosis is hCG. beta hCG values ranged from 7000 I.U. after the second exploratory curettage to 66000i.j. after four.
Since the bleeding was becoming more and more abundant, a fifth exploratory curettage was performed and the findings confirmed the diagnosis of choriocarcinoma.
Results After the last histopathological findings, the patient underwent a hysterectomy with bilateral adnexectomy, and methotrexate was included in the therapy according to the scheme.
The patient does not have distant metastases because all other findings are normal and after the second dose of chemotherapy the value of beta hcg dropped to 5000,.i.j.
Conclusion Choriocarcinoma is a rare disease, but when we have to calv after pregnancy, we have to think about this disease, because in our case we could not easily reach the correct diagnosis, so it took a long time to get the proper treatment.
Disclosures There are different prognostic systems for choriocarcinoma: the presence of metastases, level of hCG in urine and plasma, and end of last pregnancy.