Introduction/Background In recent years, due to the advances in detection and treatment,the number of women who survive breast cancer has significantly increased. However, the aggressiveness of the treatment exposes the patients to various side-effects. Itis a traumatic experience for women whichmay lead to psychiatric morbidities such as depression and anxiety.

Thepurpose of our study isto assess the prevalence and associatedfactors of depression and anxiety in breast cancer patients.

Methodology A descriptive cross-sectional study of 100womenfollowed for breast cancer in complete remission, treated in the Medical Oncology and Radiotherapy department of FarhatHachedHospital in Sousse, Tunisia. Socioeconomic variables and clinical history were collected. The psychological distress was measured through the Hospital Anxiety and Depression Scale (HADS) and the Distress thermometer scale (DTS).

Results The average age of our patients was 54 [21–72]. 53% of womenwere treated by breast conserving surgery (BCS) and 47% treated by mastectomy. Only two patients hadbreast reconstruction. The majority of our patients (81%) received chemotherapy. Well tolerated by most of them.76% of our patients received post-operative radiotherapy. 83% experienced secondary morbidities due to treatment.

An anxiety score greater than 11 was found in 59% of cases (average= 10,73 ± 4.02), a depression score greater than 11 was found in 48% of cases (average= 9.69 ± 3.88), the overall average score was20.42 ± 7.9.The results of the DTS scale show psychological distress in 45% of cases.The average DTS score was 6.4 (>5) and 12% of patients showed a score of 10.

Moderate to severe anxiety, depression, and stress were more prevalent among patients who were living in rural areas, married patients, illiterate and those treated by BCS. The score of DTS positively correlated with the HADS (p<0.001).

Conclusion Depressivedisorders, anxiety, and perceived stress are prevalent among breast cancer survivors. Our results highlighted the magnitude of the psychological pain experienced by Tunisian women

Disclosures No disclosures