Article Text
Abstract
Introduction/Background The incidence of cervical carcinoma in Serbia is 20,11/100000, which means fourth in place in Europe this year. We would like to see the incidence of abnormal Pap smears in patients with low-grade squamous intraepithelial lesions (LGSIL) compared with the colposcope findings and in relation to the year of the patient’s life
Methodology This was a retrospective study evaluating the results of the conventional Pap smear in 728 patients with LGSIL verified by analyzing samples taken by target biopsy between January 2008 and January 2012.
Results The most common colposcopy abnormal image was mosaic (39,6%), with patients who had two or more abnormal colposcopy images 24,4% patients, the acetate-white epithelium (AW) 11,9%, atypical zone transformation (AZT) had 11,2%, leucoplakia 7,1%, punctation had 3,2% and ectropion had 2,6%. Patients were from 18 to 64 years old. Distribution per age was till 20–5,9%, from 21 -30 was 40,1%, 31–40;30,1%, 41–50;18,5% and over 51;5,4% patients. The number of patients with abnormal Pap smear compared to colposcope images was: ectopia;42%, a typic transformation zone;46,4%, two or more colposcopy images; 46,6, AW 35,3%, leukoplakia; 28,3%, punctuation (ATZ); 16,6% and mosaic 13,9%. Incidence of abnormal Pap smear in patients till 20 years was 25%, from 21 -30 years was 67,3%, from 31 to 40 years was 27,6% and from 41–50 29,6% and over 50 was 38,5%.
Conclusion Our study showed that patients with LGSIL had abnormal Pap smears usually in populations from 21 to 30 years old and in groups who had two or more different colposcopy findings. This is very important because we need to extract this population in the beginning stadium of dysplasia for better and more intensive monitoring.
Disclosures Routine screenings in our country are cytology and coloscopy. Our problems are limited resources (women do not come to the examination) and HPV testing is not covered by regular insurance.