Introduction/Background Opportunistic salpingectomy is considered as a preventive tool for future ovarian and peritoneal malignancies in both average-risk and high-risk women. But, this approach will not help patients whose fallopian tubes are already harbouring pre-invasive or invasive lesions. Hence, opportunistic screening of the tubes appears to be a more fruitful approach. Through this study, we wanted to establish the utility of fallopian tube brush cytology in identifying tubal epithelial abnormalities.

Methodology Tubal specimens collected at the time of gynaecological surgeries were sent for histopathological evaluation, along with cytological specimens collected using an endobrush from the fimbrial end of the tubes. LBC smears (SurePath) and cell blocks were performed from all the tubal cytology specimens, and the findings were correlated with the histopathology.

Results A total of 392 tubal cytology were performed, all with follow-up histopathology.

Of these 390 cases, 32 were unsatisfactory (due to reduced cellularity), 342 were benign on cytology, ten were atypical, three were suspicious, and four were positive for malignancy. All 7 cases in suspicious and positive categories were serous carcinomas on follow-up histopathology. Of the ten atypical cases, two turned out to be STILs on histopathology, 4 showed salpingitis, and 4 showed normal histology.

Conclusion This study establishes the usefullness of fallopian tube brush cytology in evaluating epithelial abnormalities of the tube,it may be proposed for opportunistic screening for high-grade serous pelvic cancers as opportunistic salpingectomy may not be feasible or acceptable in all women.

Disclosures An intramural grant from All India Institute of Medical Sciences, Jodhpur, supported the study and the authors declare no conflict of interest.