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#1069 Predictive value of peritoneal carcinomatosis index for cytoreductive surgery
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  1. Kateryna Kharchenko and
  2. Olena Postupalenko
  1. Kyiv City Clinical Oncology Center, Kyiv, Ukraine

Abstract

Introduction/Background Different cutoff values of peritoneal carcinomatosis index (PCI) were proposed for cytoreductive surgery according to the current literature. They differ broadly not only among primary localizations, but among researchers of the same pathology as well. Peritonectomy is a main time-consuming procedure during cytoreductive surgery, thus it may be helpful to predict duration of operation based on clinical data.

Methodology Retrospective analysis of operative reports of patients who received high complexity cytoreductive surgery from 2020 to 2023 years in department of minimally invasive surgery (Kyiv City Clinical Oncology Center). Descriptive statistics and automatic linear modeling were applied (IBM SPSS Statistics 23).

Results One hundred twenty-four cases were identified. Ovarian cancer patients were the majority of them (n=110; 89%). PCI range from 0 to 38 (mean 14,02±8,82), operative time – 100–800 min (mean 421±138). CA125 has a highest predictor importance for PCI. To predict duration of cytoreductive surgery three major factors were established: CA125 (predictor importance 0,54), PCI (predictor importance 0,41), lymph nodes metastases (predictor importance 0,05). Accuracy of such model was 66,7%.

Conclusion CA125 and PCI are the main factors to predict duration of surgery. Further search of additional factors may help in improvement of proposed predictive model.

Disclosures none

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