Introduction/Background In the 1970s, Griffiths proved that the residual tumour diameter in ovarian cancer after surgery is inversely proportional to the survival rate. Bristow et al studied the maximal CRS in AOC. Maximal CRS was determined by the longest residual disease diameter. Most of the studies used cut off values between 1 and 2 cm for determining maximal cytoreduction. One of the most dominant prognostic factors in determining the median survival in AOC is to undergo maximal cytoreduction. Therefore, complete cytoreduction is advised leaving no residual disease.

Methodology A prospective cohort study was carried out involving patients presenting to the University Hospitals of Leicester with AOC and undergoing CRS. The aim is to assess the surgical complexity score and the postoperative outcomes in AOC patients who underwent CRS.

Results CRS was performed for the 26 patients: 17 had interval CRS and 9 had primary CRS. Complete cytoreduction (R0) was achieved in 57.7% of the patients and suboptimal cytoreduction (R1) was performed in 15.4% of the patients. Open and close surgery were done in 26.9%. The average surgical complexity score was 4.42.

Stomas were performed in around one quarter of the patients with more patients having colostomy than ileostomy. The average duration of surgery was 292 minutes and estimated blood loss was 467 ml. The average hospital stay was 9.6 days. Most of the patients (96.2%) were admitted to the HDU following surgery and the average stay in HDU was 1.7 days. After histopathology, BRCA testing showed that 73.1% were negative and 26.9% were positive.

Conclusion In Leicester, high complete cytoreduction rates were achieved. Moreover, the postoperative complication rates were acceptable and comparable in both primary and interval CRS.

Disclosures None