Introduction/Background The aim of the study is to evaluate the association between interval from initial referral to surgery and outcome of cytoreduction, surgical complexity, perioperative morbidity and mortality in patients with metastatic ovarian cancer.
Methodology Retrospective analysis of prospectively collected data for patients with stage IIIC/IV ovarian, fallopian and primary peritoneal cancer that underwent primary cytoreductive surgery over a 10-year period at a gynaecological oncology centre in the United Kingdom. Treatment interval was defined as the time from the referral with suspected cancer to surgery.
Results A total of 157 patients underwent primary cytoreductive surgery. Cytoreduction to at least less than 10 mm residual disease was achieved in 141 (89.8%) patients. The mean interval between the initial referral and surgery was 37 days (SD 2.49). The surgical complexity score was low, intermediate and high in 5 (3.5%), 18 (12.7%) and 118 (83.6%) cases, respectively. There was no association between delay in performing surgery and complexity of surgery. The interval between the initial referral and surgery was not significantly associated with the cytoreductive outcome, rate of grade 3 or 4 complications or length of hospital stay.
Conclusion Timing interval from initial referral to surgery does not appear to adversely affect morbidity or mortality in patients with metastatic ovarian cancer.
Disclosures No disclosures
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