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Poster/ePoster Sessions
06. Ovarian cancer
#327 Reproductive outcomes after fertility sparing surgery for ovarian cancer
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  1. Marta Heras1,
  2. María Alonso- Espías2,
  3. Octavio Arencibia3,
  4. Lucas Minig4,
  5. Lola Martí5,
  6. Maria Dolores Diestro2,
  7. Juan Céspedes6,
  8. Isabel Ñiguez7,
  9. Blanca Gil- Ibañez8,
  10. Berta Díaz- Feijoó9,
  11. Antoni Llueca10,
  12. Claudia Rosado11,
  13. Sara Iacoponi12,
  14. Carlos López De La Manzanara13,
  15. Sara Morales14,
  16. Maria José Fernández Galguera15,
  17. Maria Del Mar Alcalá16,
  18. Ana Cano17,
  19. Mikel Gorostidi18 and
  20. Ignacio Zapardiel2
  1. 1Hospital Santa Cristina, Madrid, Spain
  2. 2Hospital La Paz, Madrid, Spain
  3. 3Hospital Insular Materno Infantil, Las Palmas De Gran Canaria, Spain
  4. 4IMED Hospitales, Valencia, Spain
  5. 5Hospital Bellvitge, Barcelona, Spain
  6. 6Hospital Donostia, San Sebastian, Spain
  7. 7Hospital Virgen de la Arrixaca, Murcia, Spain
  8. 8Hospital 12 de Octubre, Madrid, Spain
  9. 9Hospital Clinic, Barcelona, Spain
  10. 10Hospital de Castellón, Castellón, Spain
  11. 11Hospital de Mataró, Mataró, Spain
  12. 12Hospital Quirón, Madrid, Spain
  13. 13Hospital de Ciudad Real, Ciudad Real, Spain
  14. 14Hospital Infanta Leonor, Madrid, Spain
  15. 15Hospital de Zamora, Zamora, Spain
  16. 16Hospital de Poniente, Almería, Spain
  17. 17Hospital Fundación Alcorcón, Alcorcón, Spain
  18. 18Hospital Donostia, San Sebastián, Spain

Abstract

Introduction/Background To prove the effectivity of fertility sparing procedures in young patients with ovarian cancer at early stage by assessing the pregnancy rates and obstetrical outcomes.

Methodology We performed a retrospective multicenter study among 55 Spanish hospitals, collecting patients aged from 18 to 45 years old with diagnosis of early stage (FIGO I-II) ovarian cancer, from January 2010 to December 2019. Both epithelial and non-epithelial histologies were included. Patients met inclusion criteria for undergoing conservative management and the decision was approved on a multidisciplinary committee, after explanation of potential risks to the patient . Data on attemption of pregnancy and outcomes were collected, as were need for fertility assisted techniques and way of delivery.

Abstract #327 Figure 1
Abstract #327 Figure 1

Pregnancy rates

Results 161 patients met inclusion criteria, 77 (47.8%) were epithelial tumors and 84 (52.2%) non-epithelial tumors. 42 (26%) patients achieved term pregnancy, which were 25 with epithelial histology and 17 with non-epithelial; of them,. 30 (71.4%) patients with term pregnancy underwent surgery alone and 12 (28.6%) had additional postoperative chemotherapy. Spontaneus pregnancies were possible in 32 (76.1%) patients and 10 (23.9%) patients required in vitro fertilization. Complications were reported in only one pregnancy, which was gestational diabetes. Delivery was vaginal in 29 patients and by, cesarean section in 5 patients; the type of birth was and not reported in 8 cases. Miscarriages were present in 4 patients. 9 patients had unsuccessful attemption of pregnancy, being miscarriages or inability of getting pregnant.

Conclusion Fertility sparing management for ovarian cancer seems to be an option with proven good pregnancy rates and low complication profiles. While non- epithelial tumors can be offered conservative procedures even in advanced stages with the addition of neoadjuvant chemotherapy, the selection of epithelial tumors must be under strict criteria in order to maintain good prognosis.

Disclosures None

https://doi.org/10.1136/ijgc-2023-ESGO.560

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