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#132 Incidence of lymphatic metastases in women with ovarian cancer
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  1. Anita Ganovska and
  2. Stefan Kovachev
  1. Millitary Medical Academy, Sofia, Bulgaria

Abstract

Introduction/Background The aim of our study is to determine the frequency of lymphatic metastases in women with ovarian cancer.

Methodology Material and methods: The study is single-center, retrospective for 1 year and was conducted in the Clinic of General and Oncological Gynecology, Millitary Medical Academy. All patients with histologically proven ovarian carcinoma in stage II according to TNM were included. All women underwent preoperative laboratory tests, gynecological examination with ultrasound, and preoperative imaging of the lung, abdomen, and pelvis. All patients underwent total laparohysterectomy with oophorectomy, lymphatic dissection, omentectomy and metastasectomy.

Results In our study were included 37 female patients with an average age of 53.4 years (from 26 to 89 years). Serous ovarian carcinoma was diagnosed in 24 (64.9%) patients, 5 (13.5%) endometrioid ovarian cancer, 3 (8.1%) – clear cell ovarian cancer, 3 (8.1%) – mucinous ovarian cancer, 1 (2.7%) – neuroendocrine ovarian cancer, 1 (2.7%) – small cel ovarian cancerl. A total of 275 lymph nodes were removed, or an average of about 14.9 lymph nodes per patient. Nodal metastasis were detected in 8 (21.6%) patients. Six (75%) of patients with lymph metatstases had a serous ovarian carcinoma while in 1 (12.5%) patient was detected a clear cell carcinoma, and 1 (12.5%) an endometrioid carcinoma.

Conclusion Surgery is still an important treatment strategy for ovarian cancer, but the role of systematic lymphadenectomy for treating ovarian cancer is still controversial. Lymph node status may significantly affect the survival of patients with ovarian cancer.

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