Introduction/Background Study the relationship between the interval of pregnancy before breast cancer and prognostic factors

Methodology Study 1186 patients with breast cancer and prognostic factors. Analyze interval pregnancy before breast cancer with prognostic factors (size, nodes involvement, estrogen receptor, progesterone receptor, epidermal growth factor receptor 2, tumor subtypes)

Results Pregnancy were in 958 (80‘77%) patients, 47 (4‘90%) were non invasive and 911 (95‘09%) were invasive (p<0’05), 17 (1‘8%) were negative nodes and 880 (98‘1%) were positive nodes (p<0’05). Estrogen receptor positive in 1032 (90‘13%) and negative in 113 (9‘86%) patients. Positive progesterone receptor in 890 (77‘79%) and negative in 254 (22‘20%) patients. HER2 positive in 163 (14‘57%) and negative in 955 (85‘42%) patients.

Interval last pregnancy breast cancer more one year - two years was in 27 patients and more than two years in 807 patients.

Interval last childbirth breast cancer more one year - two years versus more two years was in estrogen receptor positive 23 (3‘2%) versus 711 (90‘8%) patients (p<0’05), progesterone receptor positive 18 (2‘85%) versus 613 (78‘28%) patients (p<0’05), HER2 positive 9 (7‘5%) versus 110 (92‘43%) patients (p<0’05)

Conclusion Interval last childbirth breast cancer more than one year - two years versus more two years influences prognostic factors for later breast

Disclosures No disclosures