Introduction/Background Endometrial cancer is a common gynecologic malignancy that usually presents at an early stage, the need for lymphadenectomy in those patients is still debatable. In addition, it occurs in old comorbid patients. So performing unnecessary lymphadenectomy in patients with low risk for lymphatic metastases should be omitted to avoid related short and long-term postoperative complications.

Methodology We used intraoperative frozen section for 62 patients with low and intermediate risk stage I endometrial cancer to evaluate the tumour histologic type, grade, depth of myometrial invasion, extension to the cervix, and ESMO risk group. According to the results of frozen section, lymphadenectomy and surgical staging were tailored.

Results Intraoperative frozen section guided us to perform lymphadenectomy for 13 patients and omitting the procedure in 49 patients. Out of 62 patients, 55 were treated adequately, 5 patients were undertreated and needed surgical restaging procedure and 2 patients were over-treated by unnecessary lymphadenectomy. The adequacy of frozen section in guiding lymphadenectomy was 88.7%.

Conclusion Intraoperative frozen section is a useful strategy to guide and tailor surgical staging in early endometrial cancer.

Disclosures none