Introduction/Background Endometrial polyps affect premenopausal and postmenopausal women. The odds of an endometrial polyp being malignant are estimated to be 1–5% of all women. This study aimed to correlate the coincidence of endometrial polyps in patients with early-stage endometrial cancer.

Methodology This was a retrospective cohort study of early-stage (FIGO stage I) patients with endometrioid endometrial cancer surgically treated between 2006 and 2020. Histological confirmation of endometrial polyps was done either by the endometrial biopsy during the preoperative work-up or by the final surgical histology of the hysterectomy specimen. The demographic characteristics of the patients were analyzed and correlated with the coexistence of both invasive and non-invasive polyps.

Results 216 patients with early-stage (FIGO stage I) endometrioid endometrial cancer underwent surgery during the study period. The mean age of the women was 62.7 years.82% (n=178) of the patients were postmenopausal. Endometrial polyps were diagnosed in 17.9% (n=38) of the above patients. The polyps were found to be malignant in 21 out of 38 patients (55.2%). In 17 out of 21 cancer-involved polyps (80.9%), the size was >1 cm.

Conclusion According to the present data, endometrial polyps especially in the postmenopausal period and with a diameter of larger than 10 millimeters, must be carefully attended due to the high rate of the coincidence with endometrial cancer.

Disclosures No conflict of interest.