Introduction/Background Background Gynecological cancers are one of the most common cancers worldwide and one of the most common cause of death in women. SENTIENDO SHREC and FIRES trial prove that Sentinel lymph-node biopsy in endometrial cancers is valid option and validated procedure and it is an alternative to routine systematic pelvic and para aortic Lymphadenectomy and there by it also reduces the chances of complications of lymphadenectomy like lymphorrhea,lymphocyst and lymphedema.

Aims and objective To assess the successful mapping, sensitivity and specificity of the sentinel node biopsy in predicting lymph node metastasis in endometrial cancer

Methodology It is a prospective observational study of 2 years done In AHPGIC. Patients with endometrial cancer was attended at OPD and included by inclusion and exclusion criteria. All the included patients underwent sentinel node procedure by ICG only and strictly adhered to MSKCC protocol. All the patients also underwent routine systamatic lymphadenectomy as indicated.Both the sentinel node biopsy and routine lymph node biopsy was to be examined by pathology without the help of ultrastaging to analyse the sensitivity and specificity of the sentinel node biopsy and validation of the sentinel node technique

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Abstract #400 Figure 1

Sentinel node identified in Near infrared fluoroscopic camera after ICG dye

Results Result Total 27 ca endometrium cases were included. successful mapping was seen in 92.5% cases and bilateral mapping in 78% cases. Sensitivity, specificity and NPV were 83%, 100%, 95.4% respectively . Most common nodes identified as sentinel nodes were external illiac and obturator node.

Conclusion Conclusion sentinel lymph node analysis in ca endometrium is a safe and effective procedure. The technique is now validated in our institute

Disclosures This study has no conflict of interest from any author. No funds were required separately for this study.