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Abstract
Introduction/Background Endometrial cancer is one of the most common gynecologycal malignancies, based on alarm symptoms disease can be diagnosed in early-stage. Preoperative risk assessment can be characterized using results of histology and imaging tests independently of performing at a general hospital or a cancer care center.
Methodology The aim of our study was to examine the predictive value of pre-operative tests comparing the results of general hospitals and our university hospital.
Two-hundred and twenty-four patients were diagnosed and operated with early-stage (FIGO I/A, I/B, II) endometrial cancer at University of Debrecen, Department of Obstetrics and Gynecology, after evaluating chest and abdominal CT, pelvic MRI, and histology, between the 1st of July 2019 and the 1st of March 2023.
We characterized the subgroups comparing them with multivariable statistical models. Significant difference was measured with p-value at 0.05 using SPSS v.23.
Results Considering radiological stage, a tendency of inverse correlation was observed between the stage of the tumor and the expertise of the radiologist evaluating the imaging test at a general hospital (p=0,07). Those patients with imaging results from a general hospital had higher upstaging on final histology (36%) than at a university hospital (25%), but the difference was not significant (p-value:0,13).
73% (14/19) of patients diagnosed with endometrial intraepithelial neoplasia or atypical complex hyperplasia preoperatively (curettage or HSC), had early-stage endometrial cancer according to final histology, and 100% (14/14) of these were done in general hospitals.
Conclusion Preoperative imaging and histological result are key factors in the precise treatment plan of endometrial cancer, but depend greatly on the level of institution the tests are performed in.
Disclosures The authors have no conflict of interest.