Introduction/Background SLN mapping is based on the concept that the lymph drains in a specific pattern, away from the tumour and therefore, if first node (the SLN), is negative for metastasis, then the nodes after the SLN should also be negative.

Methodology Since 2017 we use the sentinel lymph node technique mapped with indocyanine green (ICG) dye for the treatment of endometrial cancer. For the first 40 cases between 02. 2017 until 10.2018 we performed always radical pelvic lymphadenectomy after the SLN mapping to evaluate the method and standardized our technique. However, obtaining sufficient and high surgeons experience (at least 20 cases per year) and standardized technique continues to be essential to preserving diagnostic accuracy

Results The following years between 11.2018 until 03.2023 we performed in 127 cases (101 endometrioid G1 and G2 and 26 high grades endometrial cancer) ultra-staging SLN mapping, explore the pelvic, the presacral and the paraaortic areas. The overall detection rate of SLNs was for the low- and intermediate-risk patients 100%, and 98% for the high-risk patients.

Conclusion SLN mapping in high-grade endometrial cancer demonstrates similar high detection rates and diagnostic accuracy as seen in low-grade endometrial cancers. However, future studies are needed to support this suggestion by resolving potential areas of doubt and debate, especially for high-risk endometrial cancer cases

Disclosures All authors declare no conflict of interest