Introduction/Background Ultrasound-guided biopsy is a minimally invasive method that allows us to obtain samples with precision and little preparation of the patient. In addition, it offers real-time visualization of the images with access to power Doppler.

Methodology Retrospective observational study of ultrasound-guided biopsies performed between June 2022 and April 2023 in the gynecologic oncology department of the Hospital 12 de Octubre in Madrid. The biopsies were indicated by findings in imaging tests or by the onset of suspicious symptoms.

Results 17 ultrasound-guided biopsies were studied, of which 15 were transvaginal with long trucut and 2 percutaneous with short trucut. 14 of them were located in the cervix, 1 pararectal, 1 paracervical and 1 in the pubis. The mean number of cylinders obtained was 3.8. Most were well tolerated, being the mean visual analogue scale punctuation 3.55. Adverse effects were mild: 82.4% had none, 11.8% had bleeding and 5.9% had severe pain.

82.4% of the patients had a history of previous gynecologic tumor, of which 76.4% had been cervical tumors and had received radiotherapy. Most of the women who underwent biopsy were asymptomatic (38.1%), the most frequent symptoms being pain (23.8%), bleeding (23.8%) and urinary obstruction (14.3%). The lesions detected by imaging tests had a mean maximum size of 38.58 mm by MRI, CT or PET, and 31.08 mm by transvaginal ultrasound. Tumor markers were elevated in 17.6% of cases.

11 of the biopsies were performed because of a high suspicion of malignancy, of which 9 were finally malignant by histology. 76.4% of the samples were persistencies or recurrences of previous gynecologic tumors.

Conclusion Ultrasound guided biopsy is a safe and efective option to obtain in office gynecological biopsies.

Financial interests -Blanca Gil Ibáñez. Research supports: Roche.

-Álvaro Tejerizo García. Research supports: Medtronic, Storz. Receipt of honoraria: Baxter.