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#1046 Oncologic and obstetric outcomes following laparoscopic radical trachelectomy – a single centre experience
  1. Christina Pappa,
  2. Sarah Louise Smyth,
  3. Sanjiv Manek,
  4. Sunanda Dhar,
  5. Zoe Traill and
  6. Moiad Alazzam
  1. Oxford University Hospitals, NHS Foundation Trust, Oxford, UK


Introduction/Background Cervical cancer is the fourth gynaecological cancer amongst women worldwide with one third of new cases being women between 20 and 40 years old. Nowadays, the societal progress along with economic insecurity and pursuing of higher educational and career development have led to delayed childbearing.Hence, an increasing desire for fertility sparing options has emerged. Aim of our study was to evaluate the oncologic and obstetric outcomes of laparoscopic radical trachelectomy with pelvic lymph node assessment in women with cervical tumour size less than 4cm (IB1 FIGO 2009)

Methodology Medical records of women who underwent laparoscopic radical trachelectomy with pelvic lymphadenectomy for early-stage cervical carcinoma between March 2010 and March 2019 were reviewed retrospectively. Clinicopathological variables, oncologic and obstetric outcomes were evaluated.

Results A total of 18 patients were included. The median age at initial diagnosis was 32 years (range 23–43). All patients had a FIGO stage Ib1 disease in the final histopathology examination and none them received adjuvant therapy. Median follow up was 87.5 months (range 44–120). One recurrence (5.5%) recorded 27 months after completion of initial treatment and no death was recorded during the time of the study. The overall survival rates were 100%. (95% CI, 97.6–99.7) Seven women attempted to conceive during the study period and they all achieved a clinical pregnancy. Among the patients who have attempted a pregnancy, the live birth rate was 71,4%.

Conclusion Our study showed that laparoscopic radical trachelectomy seem to be favorable in meticulously selected patients who desire to preserve their fertility. Future research will hopefully provide further insight into more accurate selection criteria and minimally invasive surgical mode to achieve maximal obstetric outcomes without jeopardizing the oncologic outcomes.

Disclosures No

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