Introduction/Background Malignant peripheral nerve sheath tumours (MPNSTs) represent only approximately 10 per cent of tumours of peripheral origin, their incidence is 0.001 per cent .
MPNSTs more frequently are found on the extremities and trunk, and less often on the head and neck [2,3]. Clinically they usually present with pain, growth of tumorous mass and neurologic deficit . Rapid tumour growth is suggestive of malignancy . Diagnosis is achieved with radiologic techniques and tissue biopsy which is particularly important to differentiate malignancy.
MPNSTs of the uterine cervix are extremely rare, they usually present as a large exophytic mass on the uterine cervix. Treatment protocols vary because of the rarity of the disease and besides surgery, adjuvant radiation and chemotherapy should be considered.
Case report We present a case of a 51 years old patient admitted to our institution due to severe uterine bleeding and a polypoid large exophytic cervical lesion 7x4cm, by mistake these lesions are often misjudged as protruding leiomyoma. Excision of the cervical tumorous mass was performed. Immunohistochemistry was positive for vimentin, S-100 and Ki 67. Two years before right quadrantectomy was performed due to breast carcinoma for which radiation and hormonal therapy is given. Computed tomography of the thorax showed no signs of metastasis or residual disease, in the abdomen and pelvis wathe s noted cervical mass, but no enlarged lymph nodes were noted. The patient is appointed for surgery, perioperative exams are appointed.
Conclusion MPNSTs of the uterine cervix are an extremely rare group of sarcomas, only 16 cases are reported in the literature, because of their rarity treatment protocols vary, surgery by radical hysterectomy is the prefered choice, and adjuvant therapy by radiation and chemotherapy is individual.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.