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2022-RA-787-ESGO ESGO guidelines on the management of endometrial cancer. Weaknesses and controversies in france and french-speaking switzerland. Results of a delphi survey
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  1. Carolin Marti1,2,
  2. Elise Deluche3,
  3. Floriane Jochum4,5,
  4. Sofiane Bendifallah6,
  5. Henri Azaïs7,
  6. Jonas Deidier8,
  7. Vincent Cockenpot9,
  8. Inès Menoux10,
  9. Vincent Balaya11,
  10. Sarah Betrian12,
  11. Cyrus Chargari13,
  12. Sebastien Gouy14,
  13. Catherine Genestie15,
  14. Catherine Uzan16,17,
  15. Frederic Guyon18,
  16. Mojgan Devouassoux-Shisheboran19,
  17. Noémie Body20,
  18. Cherif Akladios5,
  19. Patrice Mathevet21 and
  20. Benedetta Guani2,21
  1. 1Ecole doctorale, UNIL, Lausanne, Switzerland
  2. 2Department of Gynecology and Obstetrics, HFR, Fribourg, Switzerland
  3. 3Department of Medical Oncology, CHU Limoges, Limoges, France
  4. 4Department of Gynecology, Institut Curie, Université Paris-Saclay, Paris, France
  5. 5Department of Gynecology and Obstetrics, Hopitaux Universitaires de Strasbourg, Strasbourg, France
  6. 6Department of Gynecology, Tenon Hospital, Paris, France
  7. 7Gynecologic and Breast Oncologic Surgery Department, Georges Pompidou European Hospital, Paris, France
  8. 8Department of Radiology, Hôpital Universitaire Paris Ouest Site G Pompidou APHP, Paris, France
  9. 9Department of Pathology, Centre Léon Bérard, Lyon, France
  10. 10Department of Radiotherapy, ICANS, Strasbourg, France
  11. 11Department of Gynecology, Foch Hospital, Suresnes, France
  12. 12Department of Medical Oncology, IUCT Oncopole, Toulouse, France
  13. 13Department of radiation oncology, Gustave Roussy, Paris, France
  14. 14department of Surgical gynecology oncology, Gustave Roussy, Paris, France
  15. 15Department of Pathology, Gustave Roussy, Paris, France
  16. 16Departement of gynecology and obstetrics, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France
  17. 17Institut Universitaire de cancérologie, Sorbonne Université, Paris, France
  18. 18Department of Surgical Oncology, Bergonié Institute, Bordeaux, France
  19. 19Department of Pathology, Hospices civiles de Lyon, Lyon, France
  20. 20Department of Surgical Oncology, Institut de Cancérologie de l’Ouest (ICO), Angers, France
  21. 21Department of Gynecology and Obstetrics, CHUV, Lausanne, Switzerland

Abstract

Introduction/Background To assess the opinion of a panel of experts and obtain consensus on several issues from the ESGO recommendations on the management of endometrial cancer.

Abstract 2022-RA-787-ESGO Table 1

List of recomendations

Methodology A Delphi survey was carried out among a panel of French and French-speaking Swiss experts. The questionnaire included 58 questions divided into 8 categories: characterization of experts, histo-molecular characteristics, radiological data, management of low-risk, intermediate-risk, intermediate-high-risk, high-risk and metastatic cancers. The experts were asked to reply on a 9-point scale, both on the validity and the clarity of each suggestion. After the answers were analysed, a second round was sent to the same experts for selected suggestions. To be accepted, each proposal had to obtain a median greater than or equal to 7/9.

Results The study was conducted between December 2021 and March 2022. 58 (57.4%) of 101 experts responded in the first round and 41 proposals were found. 5 questions were voted redundant and 19 discordant. These questions were reworded and partially split and at the end of the 2nd round, out of the 20 proposals 16 were validated and 4 rejected. In total, the study presents an analysis of 61 questions.

Conclusion These consensual recommendations are expected to standardize the management of endometrial cancer in France and French-speaking Switzerland and to optimize clinical practices.

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