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TP008/#1422 Epidemiological landscape of cervical cancer in Latin America (EVITA LATAM) – LACOG 0820
  1. Graziela Zibetti Dal Molin1,2,
  2. Mivael Olivera3,
  3. Adrian Guerrero4,
  4. Reitan Ribeiro5,
  5. Juan Zarba6,
  6. Andreia Cristina De Melo2,7,
  7. Gustavo Werutsky8,
  8. Heloisa De Andrade Carvalho9,
  9. Juan Velasquez10,
  10. Alexssandra Siqueira Dos Santos7,
  11. Fernanda Damian2,11,
  12. Eduardo Cronemberg12,
  13. André Mattar13,
  14. Lucely Cetina-Perez14,
  15. Miriam Raimondo15,
  16. Natalia Baltz Hehn16,
  17. Ronaldo Schmidt17,
  18. Vanessa Bezerra18,
  19. Rafaela De Jesus19,
  20. Taiane Rebelatto2 and
  21. Renata Colombo Bonadio20,21
  1. 1Hospital Beneficência Portuguesa de São Paulo, Medical Oncology, São Paulo, Brazil
  2. 2Latin American Cooperative Oncology Group (LACOG), Oncology, Porto Alegre, Brazil
  3. 3Instituto Nacional de Enfermedades Neoplásicas, Gecoperu, Lima, Peru
  4. 4Universidad Autónoma de Santo Domingo (UASD), Instituto Nacional del Cáncer Rosa E. Sánchez (INCART), Oncology, Santo Domingo, Dominican Republic
  5. 5Erasto Gaertner Hospital, Oncology, Curitiba, Brazil
  6. 6Centro Medico San Roque Exelsus, Oncología Clínica, San Miguel de Tucumán, Argentina
  7. 7Instituto Nacional de Câncer, Oncologia Clínica, Rio de Janeiro, Brazil
  8. 8Latin America Cooperative Oncology Group, Chair, Porto Alegre, Brazil
  9. 9Hospital das Clínicas da Universidade de São Paulo, Oncology, São Paulo, Brazil
  10. 10Instituto Nacional Cancerologia, Oncology, Bogotá, Colombia
  11. 11Hospital São Lucas da PUCRS, Oncology, Porto Alegre, Brazil
  12. 12Centro Regional Integrado de Oncologia (CRIO), Oncology, Fortaleza, Brazil
  13. 13Hospital Pérola Byington, Oncology, São Paulo, Brazil
  14. 14Instituto Nacional Cancerologia (INCAN), Gynecology Oncology, Ciudad de México, Mexico
  15. 15Sanatorio de La Mujer, Oncology, Rosario, Argentina
  16. 16Fundación CENIT, Oncology, Buenos Aires, Argentina
  17. 17Barretos Cancer Hospital, Oncology, Barretos, Brazil
  18. 18Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, Ginecologia Oncológica, São Paulo, Brazil
  19. 19Latin America Cooperative Oncology Group, Statistics, Porto Alegre, Brazil
  20. 20Instituto do Cancer do Estado de Sao Paulo, Medical Oncologist, São Paulo, Brazil
  21. 21Faculdade de Medicina da Universidade de São Paulo, Oncology, São Paulo, Brazil


Objectives Cervical cancer is highly incident in Latin America (LATAM) and is frequently diagnosed in advanced stages. There is scarce information on clinical and epidemiological aspects of cervical cancer in LATAM. This study will provide data to develop comprehensive programs to improve cervical cancer prevention and treatment in the region.

Methods LACOG 0820 (EVITA LATAM) is an observational retrospective and prospective study that aims to characterize cervical cancer in LATAM. Patients from 16 research sites in 7 LATAM countries (Argentina, Brazil, Costa Rica, Dominican Republic, Mexico, Peru, Colombia), diagnosed with cervical cancer of any histology, FIGO 2018 stage IB2 or greater, since Jan 2018 or newly diagnosed during recruitment will be included. The factors to be evaluated comprise demographic and socio-economic (patient’s country, occupation, income, educational level, marital status, health insurance coverage) and clinical aspects (histology, stage at diagnosis, smoking history, hemoglobin level, renal function, time from diagnosis to initiation of definitive treatment for localized disease). Data will be collected from medical charts during 5 years from diagnosis. Tumor block will be collected from patients who agree at time of ICF signature for exploratory analyses. A biorepository will be established to perform next generation sequence tests and describe tumor molecular characteristics. Based on prevalence of locally advanced cervical cancer in LATAM, 482 patients are expected to be enrolled in this study. As of 30 June 2022, 131 patients had been enrolled. NCT04947605

Results Trial in progress: no available results at submission.

Conclusions Trial in progress: no available conclusions at submission.

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