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2022-RA-1385-ESGO Total laparoscopic radical hysterectomy versus laparoscopic-assisted vaginal radical hysterectomy for the treatment of early-stage cervical cancer
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  1. Luka Kovac1,2,
  2. Branko Cvjetićanin1,
  3. Vid Janša1,2,
  4. Špela Smrkolj1,2,
  5. Borut Kobal1,2 and
  6. Leon Meglič2,1
  1. 1Department of Gynaecology, University Medical Centre Ljubljana, Ljubljana, Slovenia
  2. 2Medical Faculty, University of Ljubljana, Ljubljana, Slovenia

Abstract

Introduction/Background Prevention of cervical cancer is a story of progress in the western world. Globally, however, it still represents a vital disease burden. The approach to surgical treatment of early-stage disease has changed dramatically in recent years. We present data in our center before the LACC trial.

Methodology A retrospective, observational study of a single tertiary level center between January 2011 and December 2016. Clinical data were gathered from the Division of Gynaecology and Obstetrics archive, University Medical Centre Ljubljana.

Results A total of 52 patients underwent minimally invasive surgery in that period. In thirty-two cases, laparoscopic-assisted vaginal radical hysterectomy was performed, and total laparoscopic radical hysterectomy in twenty cases. There was no statistically significantdifference in clinical characteristics or overall survival and disease-free survival between LAVRH and TLRH. In the follow-up of 60 months, 8 (15,4%) recurrences were observed. Of those, 4 (12,5%) were in LAVRH group and 4 (25,0%) in TLRH. In the follow-up period of 60 months, there were 4 (7,7%) deaths, 2 (6,3%) in the LAVRH group and 2 (10,0%) in the TLRH group, all of which were related to recurrences.

Abstract 2022-RA-1385-ESGO Figure 1

Kaplan-meier disease-free survival curves for LAVRH and TLRH

Conclusion A non-significant trend towards worse outcomes in the TLRH subgroup was observed. Results are similar to those reported in the prospective and retrospective analysis since 2018.

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