Introduction/Background Cervical cancer is a global public health problem. It causes significant morbidity and mortality, with more than 500,000 new cases and more than 300,000 deaths per year worldwide. In Tunisia, we do not have enough published data, so the epidemiological profile of this pathology is not well known. The objective of this work was to determine the epidemiological profile of cervical cancer in Tunisia and to specify the cost of treating the disease in order to develop an effective prevention strategy.

Methodology This was a retrospective descriptive, multi-centric study conducted in 6 obstetrical gynecology departments over a four-year period from January 1, 2016 to December 31, 2019.

Results The number of all-stage cervical cancer cases in the different centers was 665 cases over a four-year period; which is equivalent to 166 cases/year. The average age of our patients was 53.5 years. Cervico-vaginal smear screening was performed in only 17.9% of cases. The average consultation time in the study population was 5.6 months. Tumors were classified according to the FIGO 2009 c: 23.5% were diagnosed at an early stage (<IB1) and 76.3% at advanced stages (IB2 up to IV). Several therapeutic sequences were applied in our study, the most frequent was surgery associated with radiotherapy and chemotherapy (60.1%). Surgery was performed in 69.6% of patients . Radiotherapy was performed in 84.6% of patients. Brachytherapy was performed in 72% of cases . The direct annual cost of treatment was estimated at 1,268,502 $. Radiotherapy represented the largest item of expenditure .

Conclusion Cervical cancer still poses problems in terms of treatment due to the late diagnosis of this pathology. The control of this pathology of infectious origin necessarily involves the implementation of a mass vaccination against HPV of young girls who have not yet had sexual relations.