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Vaginal and vulvar cancer
2022-RA-1099-ESGO Impact of age on surgical resection margins of vulvar squamous cell carcinoma: multicenter descriptive study
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  1. Emilie Raimond1,
  2. Caroline Ambroise2,
  3. Camille Mimoun3,
  4. Yohan Kerbage4,
  5. Lobna Ouldamer5,
  6. Sofiane Bendifallah6,
  7. Xavier Carcopino7,
  8. Martin Koskas8,
  9. Pierre adrien Bolze9,
  10. Lavoue Vincent10,
  11. Tristan Gauthier11,
  12. Arnaud Fauconnier12 and
  13. Cyrille Huchon13
  1. 1Gynaecology, CHU de REIMS, REIMS, France
  2. 2Department of Obstetrics and Gynaecology, Institute Alix de Champagne University Hospital, REIMS, France
  3. 3Department of Obstetrics and Gynaecology, Lariboisière hospital, Paris, France
  4. 4Department of Obstetrics and Gynaecology, Lille University Hospital, Lille, France
  5. 5Department of Obstetrics and Gynaecology, Regional University Hospital Center of Tours, TOURS, France
  6. 6Department of Obstetrics and Gynaecology, Tenon hospital, Paris, France
  7. 7Department of Obstetrics and Gynaecology, North Hospital, Marseille, France
  8. 8Department of Obstetrics and Gynaecology, Bichat hospital, Paris, France
  9. 9Department of Gynecological Surgery and Oncology, Pierre Bénite Hospices Civils de Lyon, Lyon, France
  10. 10Department of Obstetrics and Gynaecology, University Hospital Center of Rennes, South Hospital, Rennes, France
  11. 11Department of Obstetrics and Gynaecology, Mère – enfant Hospital, University Hospital Center of Limoges, Limoges, France
  12. 12Department of Obstetrics and Gynaecology, Intercommunal Hospital Center of Poissy, Poissy, France
  13. 13Intercommunal Hospital Center of Poissy, lariboisière Hospital, Paris, France

Abstract

Introduction/Background Vulvar cancer is a rare cancer that most often affects elderly women and is therefore vulnerable. The first-line treatment for vulvar cancer is surgery. Histological resection margins ≥ 8 mm are recommended. The aim of this study was to assess the impact of patient age on the size of surgical resection margins for vulvar cancer.

Methodology This is a multicenter retrospective observational study of 596 cases of vulvar squamous cell carcinoma. An age limit of 65 years was chosen to define the 2 groups of patients to be compared.

Results Patients < 65 years old presented clinically smaller tumors than older patients. Surgically, more patients benefited from total radical vulvectomy in the group ≥ 65 years (28.2% (n=107) versus 20.3% (n=44), p=0.04). The mean postoperative lesion size was 29.3 mm (2–120) in the group < 65 years old versus 32.3 mm (1–150) in the group ≥ 65 years old (p = 0.044). The proportion of excision in sano was similar and there was no difference in obtaining margins > 8 mm between the 2 groups. However, more patients required revision surgery in the group < 65 years.

Conclusion Despite a larger tumor size depending on the age of the patients, age is not a factor influencing the obtaining of resection margins > 8 mm.

https://doi.org/10.1136/ijgc-2022-ESGO.949

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