2022-RA-701-ESGO Elucidating mechanisms underlying methotrexate resistance via quantitative proteomics analysis of GTN patient samples and choriocarcinoma cell lines: a crucial role for serine metabolism

Panagiota Ntavelou; Marina Georgiou; Geoffrey Maher; Rajat Roy; Sijia Yu; Paul Ajuh; Baljeet Kaur; Neil Horowitz; Ross S Berkowitz; Kevin Elias; Michael J Seckl; Olivier E Pardo

doi:10.1136/ijgc-2022-ESGO.904

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Trophoblastic diseases

2022-RA-701-ESGO Elucidating mechanisms underlying methotrexate resistance via quantitative proteomics analysis of GTN patient samples and choriocarcinoma cell lines: a crucial role for serine metabolism

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Authors

Panagiota Ntavelou Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK PubMed articles Google scholar articles
Marina Georgiou Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK PubMed articles Google scholar articles
Geoffrey Maher Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK Trophoblastic Tumour Screening and Treatment Centre, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK PubMed articles Google scholar articles
Rajat Roy Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK PubMed articles Google scholar articles
Sijia Yu Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK PubMed articles Google scholar articles
Paul Ajuh Gemini Biosciences, Liverpool, UK PubMed articles Google scholar articles
Baljeet Kaur Trophoblastic Tumour Screening and Treatment Centre, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK PubMed articles Google scholar articles
Neil Horowitz Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA PubMed articles Google scholar articles
Ross S Berkowitz Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA PubMed articles Google scholar articles
Kevin Elias Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA PubMed articles Google scholar articles
Michael J Seckl Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK Trophoblastic Tumour Screening and Treatment Centre, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK PubMed articles Google scholar articles
Olivier E Pardo Division of Cancer, Department of Surgery and Cancer, Imperial College, London, UK PubMed articles Google scholar articles

Citation

Ntavelou P, Georgiou M, Maher G, et al

International Journal of Gynecologic Cancer 2022;32:A421.

Publication history

First published October 20, 2022.

Online issue publication

October 27, 2022

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