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2022-RA-1005-ESGO Invasive cervical cancer of one cervix in uterus didelphys type of uterine anomaly – a case report and review of the literature
  1. Miroslav Popovic,
  2. Milica Pajic and
  3. Zvjezdana Ritan Micic
  1. Clinic of Gynecology and Obstetrics, The University Clinical Centre of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina


Introduction/Background Throughout the development of the urogenital system, the Müllerian ducts have a crucial role. In the beginning, they are found in both sexes, but they regress under the impact of the anti-Müllerian hormone (AMH). Without the involvement of AMH, the ducts evolve into the uterus, uterine tubes, cervix, and upper portion of the vagina. Anomalies of the Müllerian ducts are more frequent than imagined, varying from 0.5 to 6.7% in the general population and up to 16.7% in women diagnosed with recurrent miscarriage.

Methodology The authors report a case of invasive adenosquamous cervical cancer of one cervix in uterus didelphys type of a uterine abnormality (double uterus, double cervix), along with a review of the literature.

Results The 50-year-old patient was diagnosed, then surgically treated with a Wertheim-Meigs radical hysterectomy. Fifteen lymph nodes were removed during the surgery and examined under the microscope, but they showed no presence of the tumor cells. Except for adhesion removal between the bladder and rectum in the middle line, surgery was open, conducted traditionally, and as described in the literature. Postoperative care went without any complications, and the patient was discharged from the clinic on time. The histopathological analysis classified the tumor as IB1 gradus I. Adjuvant radiotherapy was suggested and also performed after the definite pathohistological diagnosis.

  • adenosquamous cervical cancer
  • uterus didelphys
  • uterus duplex
  • cervix duplex
  • Wertheim-Meigs radical hysterectomy

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