Introduction/Background Seven out of ten people in Brazil depend exclusively on the Brazilian Public Health System (SUS). More than 150 millions of Brazilian citizens has no private health insurance. It is estimated approximately 1 in 300 people have hereditary breast and ovarian cancer syndrome (HBOC) and 1 in 300 people also have Lynch syndrome. The objective of our study is to describe the number of families enrolled in the Pernambuco Public Hereditary Cancer Program tested for germline cancer predisposition variants.

Methodology Our study is an exploratory study based on data from a retrospective analysis of hospital records, with patients enrolled in the Public Hereditary Cancer Program of 3 hospitals in Pernambuco: Hospital de Cancer de Pernambuco (HCP), Instituto de Medicina Integral Professor Fernando Figueira (IMIP) and Barão de Lucena’s Hospital, from November 2016 to April 2022.

Results 1092 families met the NCCN criteria for hereditary cancer syndromes, almost 90% of then were HBOC or Lynch syndromes. No patient or family has been tested for germline cancer predisposition variants funded for the Brazilian Public Health System (SUS).

Conclusion The identification of hereditary cancer predisposition would give patients and non-affected high-risk relatives the possibility of screening for malignant neoplasms with onset at earlier ages and different follow up than in the general population such as risk-reducing surgeries, when indicated. Unfortunately, no patient or family from Pernambuco Public Hereditary Cancer Program has been tested for germline cancer predisposition variants funded for the Brazilian Public Health System (SUS).