Introduction/Background In Algeria, breast cancer has become a major public health problem with a real urgency of intervention and management. The aim of this work was to analyse the epidemiological, clinical, therapeutic and evolutionary particularities of breast cancer in young women under the age of 30.

Methodology This is a retrospective cohort of 35 patients under 30 years of age with breast cancer who were treated at the radiotherapy department of the cancer center Tlemcen, Algeria between September 2017 and August 2021.

Results The median age was 28 (20–30) years, the left breast was affected in 51.4% of cases (18 patients) and the external site of the tumor predominated in 45.7% of cases (16 patients). 85.7% of patients had invasive ductal carcinoma. The tumors were classified as T1 in 25.7%, T2 in 57.1%, T3 in 8.5% and T4 in 8.5% of cases. 51.4% of the cases had lymph node involvement and the median histological size was 35 mm (0 -70). 29 patients (82.8%) underwent radical surgery (patey) and 6 patients (17.1%) underwent conservative surgery. Chemotherapy was used in 11.4% of cases as neoadjuvant and in 88.5% of cases as adjuvant. 25 patients (71.4%) received adjuvant hormonal therapy and 12 patients (34.2%) received targeted therapy. Locoregional radiotherapy was delivered in all patients at a biological dose of 50GY to the chest wall, supra and subclavicular lymph nodes ± tumor bed boost. Dermatitis was found in 100% of cases, dysphagia in 22.8%, pain in 20%, fibrosis in 14.2% and edema in 14.2% of cases. The median follow-up was 24.5 months (1- 49) with only one metastatic relapse.

Conclusion Although our series showed satisfactory results, breast cancer in young women remains of unfavorable prognosis.